Platelet Inhibition, Plavix

Hematology

LAB5210327

PLAVIX
P2Y12

VerifyNow special tubes provided by, and drawn by, Laboratory. See Instructions/Remarks below for proper procedure for drawing blood. WALK SPECIMENS DOWN TO LAB

Collection of blood sample should be performed with care to avoid hemolysis or contamination by tissue factors. 1) Set up a discard tube -- may be red-top (no additive), blue, blood culture, or heparin tube. The discard tube cannot contain EDTA (lavender top). 2) VerifyNow collections tubes are Greiner Bio-One Vacuette partial-fill blood collection tubes (2 mL fill volume) containing 3.2% sodium citrate. 3) Obtain samples from extremity free of IV infusions. 4) If drawing for a CBC at the same time, FILL THE CBC TUBE LAST to avoid contaimination by EDTA. 5) Collect whole blood using a 21 guage or larger needle. Butterfly (21 guage) is okay. 6) First tube is the 'discard tube' (at least 2 mL), second and third tubes are the VerifyNow tubes. 7) Fill the second tube (VerifyNow) to the black line (approx. 1/2 of the tube. Do not under or overfill.) Fill the third VerifyNow tube to the black line. 8) Gently invert the tubes at least 5 times to ensure complete mixing. 9) Send the 'Discard Tube'to the Lab with the VerifyNow tubes. 10) DO NOT SEND VERIFYNOW TUBES TO THE LAB VIA THE TRANSLOGIC TUBE SYSTEM. Hand deliver, Ambient:. LAB: Test must be performed within 4 hours of collection. Do NOT centrifuge tubes.

Ambient

Ambient 4 hrs

Hemolyzed, contanminated, clotted, not enough volume

Draw between 7am and 7pm

Testing available 7am - 7pm Reports same shift.

P2Y12 Assay: (PRU - P2Y12 Reaction Units)
Reference Range 194 - 418 PRU
PRU result of < 194 indicates that there evidence of a P2Y12 platelet receptor blockage by Clopidogrel (Plavix).