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Platelet Inhibition, Plavix
MessageHematology
Test Code
LAB5210327
Alias/See Also
PLAVIX
P2Y12
P2Y12
CPT Codes
85576
Preferred Specimen
Must be drawn by Lab Phlebotomist using VerifyNow Greiner Bio-One Vacuette partial-fill blood collection tubes (contact Lab to obtain).
See Instructions/Remarks below for proper procedure for drawing blood.
Must be hand delivered to the Laboratory, do NOT use pneumatic tube to send specimen.
See Instructions/Remarks below for proper procedure for drawing blood.
Must be hand delivered to the Laboratory, do NOT use pneumatic tube to send specimen.
Instructions
Collection of blood sample should be performed with care to avoid hemolysis or contamination by tissue factors.
1) Set up a discard tube -- may be red top tube (no additive), blue top tube, blood culture bottle, or heparin tube. The discard tube cannot contain EDTA (lavender top).
2) VerifyNow collections tubes are Greiner Bio-One Vacuette partial-fill blood collection tubes (2 mL fill volume) containing 3.2% sodium citrate.
3) Obtain samples from extremity free of IV infusions.
4) If drawing for a CBC at the same time, FILL THE CBC TUBE LAST to avoid contaimination by EDTA.
5) Collect whole blood using a 21 guage or larger needle. Butterfly (21 guage) is okay.
6) First tube is the 'discard tube' (at least 2 mL), second and third tubes are the VerifyNow tubes.
7) Fill the second tube (VerifyNow) to the black line (approx. ½ of the tube. Do not under or overfill.) Fill the third VerifyNow tube to the black line.
8) Gently invert the tubes at least 5 times to ensure complete mixing.
9) Walk down to the lab the 'Discard Tube' and the VerifyNow tubes.
10) DO NOT SEND VERIFYNOW TUBES TO THE LAB VIA THE PNUEMATIC TUBE SYSTEM.
Hand deliver, ambient.
LAB: Test must be performed within 4 hours of collection. Do NOT centrifuge tubes.
1) Set up a discard tube -- may be red top tube (no additive), blue top tube, blood culture bottle, or heparin tube. The discard tube cannot contain EDTA (lavender top).
2) VerifyNow collections tubes are Greiner Bio-One Vacuette partial-fill blood collection tubes (2 mL fill volume) containing 3.2% sodium citrate.
3) Obtain samples from extremity free of IV infusions.
4) If drawing for a CBC at the same time, FILL THE CBC TUBE LAST to avoid contaimination by EDTA.
5) Collect whole blood using a 21 guage or larger needle. Butterfly (21 guage) is okay.
6) First tube is the 'discard tube' (at least 2 mL), second and third tubes are the VerifyNow tubes.
7) Fill the second tube (VerifyNow) to the black line (approx. ½ of the tube. Do not under or overfill.) Fill the third VerifyNow tube to the black line.
8) Gently invert the tubes at least 5 times to ensure complete mixing.
9) Walk down to the lab the 'Discard Tube' and the VerifyNow tubes.
10) DO NOT SEND VERIFYNOW TUBES TO THE LAB VIA THE PNUEMATIC TUBE SYSTEM.
Hand deliver, ambient.
LAB: Test must be performed within 4 hours of collection. Do NOT centrifuge tubes.
Transport Temperature
Ambient
Specimen Stability
Ambient 4 hrs
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed, contaminated, clotted, underfilled – QNS, spun down, sent in pneumatic system
Setup Schedule
Testing performed 7 AM – 7 PM
Specimens must be drawn within this timeframe.
Specimens must be drawn within this timeframe.
Report Available
Testing available 7am - 7pm Reports same shift.
Reference Range
P2Y12 Assay: (PRU – P2Y12 Reaction Units)
Reference Range 182 - 335
PRU of < 182 indicate evidence of a P2Y12 inhibition by a medication such as Clopidogrel (Plavix)
Reference Range 182 - 335
PRU of < 182 indicate evidence of a P2Y12 inhibition by a medication such as Clopidogrel (Plavix)
