Alpha Globin Cluster Locus Deletion/Duplication, Varies

Message

Sendouts, Mayo test code: AGDD

Test Code

LAB1238245

Alias/See Also

AGPB
Alpha Globin
Alpha Thalassemia
Alpha-Thalassemia
ATHAL
HBA1
HBA2
Hemoglobin Bart
Hemoglobin-H Disease
Hydrops Fetalis
Thalassemia, Alpha
ABC
AGDD

CPT Codes
81269

Preferred Specimen

3 mL whole blood in a lavender EDTA or yellow ACD tube.

Minimum Volume

Whole blood: 1 mL
Amniotic fluid: 10 mL

Other Acceptable Specimens

Saliva collected in a swab collection kit (T786)
Amniotic fluid: 20 mL
Confluent cultured cells

Instructions

Specimen preferred to arrive within 96 hours of collection.

Transport Container

Original container

Transport Temperature

Ambient

Specimen Stability

Blood Ambient (preferred): 4 days, Refrigerated: 14 days
Saliva Ambient: 30 days

Methodology
Dosage Analysis by Polymerase Chain Reaction (PCR)/Multiplex Ligation-Dependent Probe Amplification (MLPA)

Setup Schedule

Monday, Wednesday

Report Available

9-13 days

Reference Range

Included with report

Clinical Significance

• Diagnosis of alpha-thalassemia
• Prenatal diagnosis of deletional alpha-thalassemia
• Carrier screening for individuals from high-risk populations for alpha-thalassemia
• This test is not useful for diagnosis or confirmation of beta-thalassemia or hemoglobinopathies

Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota

Additional Information
Alpha Globin Cluster Locus Deletion/Duplication, Varies

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.