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Streptococcus pneumoniae IgG Antibodies, 23 Serotypes, Serum
MessageSendout, Mayo test code: PN23M
Test Code
LAB5210654
Alias/See Also
Pneumococcal Antibody (IgG) 23 Serotype Panel
Strep Antibodies
Strep Pneumo Antibodies
Strep Pneumoniae Antibody
Strep Vaccine
Streptococcus Pneumoniae
Vaccine
PN23M
Strep Antibodies
Strep Pneumo Antibodies
Strep Pneumoniae Antibody
Strep Vaccine
Streptococcus Pneumoniae
Vaccine
PN23M
CPT Codes
86317 x 23
Preferred Specimen
Collect 0.5mL serum from a serum gel tube
Minimum Volume
0.4 mL
Instructions
Centrifuge and aliquot serum into plastic vial
Transport Container
Plastic vial
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated (preferred): 21 days
Frozen: 21 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Gross lipemia Reject
Gross icterus Reject
Methodology
Bead-Based Multiplex Immunoassay
Setup Schedule
4 to 6 days
Report Available
Monday through Friday
Limitations
The humoral immune response to Streptococcal pneumoniae vaccination is affected by multiple factors, including age, immune status, vaccination history, prior infections, and carrier status.
Protective concentrations of IgG antibodies, or those required to prevent infection from S. pneumoniae, have not been defined for any serotype.
Quantitation of the IgG antibody response to pneumococcal serotypes does not provide any information on the functional capacity of the serotype-specific antibodies generated (opsonization efficiency).
IgG antibodies specific for the 23 serotypes included in PPSV23 are measured in this test; except for serotype 6A, IgG antibodies specific for all the serotypes in PCV13, PCV15, and PCV20 are measured in this test.
Protective concentrations of IgG antibodies, or those required to prevent infection from S. pneumoniae, have not been defined for any serotype.
Quantitation of the IgG antibody response to pneumococcal serotypes does not provide any information on the functional capacity of the serotype-specific antibodies generated (opsonization efficiency).
IgG antibodies specific for the 23 serotypes included in PPSV23 are measured in this test; except for serotype 6A, IgG antibodies specific for all the serotypes in PCV13, PCV15, and PCV20 are measured in this test.
Reference Range
Included with report
Clinical Significance
Assessing the IgG antibody response to active immunization with nonconjugated, 23-valent pneumococcal vaccines
Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 20-valent pneumococcal vaccines
Determining the ability of an individual to produce an antibody response to polysaccharide antigens, as part of the evaluation for humoral or combined immunodeficiencies
Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 20-valent pneumococcal vaccines
Determining the ability of an individual to produce an antibody response to polysaccharide antigens, as part of the evaluation for humoral or combined immunodeficiencies
Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota
Additional Information
Streptococcus pneumoniae IgG Antibodies, 23 Serotypes, Serum
