Lyme Disease Antibody with Reflex to Immunoassay (IgG, IgM)

Test Code

LAB5210996

Quest Code

39733

CPT Codes
86618

Includes

If Lyme Disease Antibody is Positive or Equivocal (≥0.91), then Lyme Disease Supplemental Antibodies (IgG, IgM), Immunoassay will be performed at an additional charge (CPT code(s): 86617(x2))

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Grossly icteric

Methodology
Immunoassay (IA)

Setup Schedule

Set up: Mon, Wed-Sat; Report available: 1-3 days

Report Available

Reports in 1 to 3 days.

Reference Range

Lyme Ab, Screen	≤0.90 index
Lyme Ab (IgG)	≤0.90 index
Lyme Ab (IgM)	≤0.90 index

Clinical Significance

Lyme disease is a growing health issue. There has been an urgency to establish an efficient testing protocol that increases sensitivity for antibodies against Borrelia burgdorferi in early disease without negatively impacting specificity. In this algorithm, serum is first tested in an immunoassay measuring combined IgG and IgM antibodies to specific borrelial proteins; if reactive, the sample is then tested in separate Borrelia burgdorferi IgG and IgM immunoassays. This algorithm may be able to assist in the identification of early Lyme disease within the first 30 days of infection.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.