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Acetylcholinesterase (NY)
Test Code10230
CPT Codes
82664
Preferred Specimen
1.5 mL amniotic fluid collected in a sterile transport tube
Minimum Volume
0.5 mL
Instructions
Collect in a sterile transport tube. Indicate gestational age, collection date, clinical indication, and the AFP and MoM results, if available, on the test requisition.
Note: This test is automatically performed on all Alpha-Fetoprotein amniotic fluids when the MoM is greater than 1.00.
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 4 months
Frozen: 3 years
Refrigerated: 4 months
Frozen: 3 years
Methodology
Gel Electrophoresis
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
This test code is for New York patient testing. For non-New York patient testing, use test code 4929.
Setup Schedule
Monday, wednesday and friday
Report Available
4 days
Reference Range
Negative
Clinical Significance
The presence of Acetylcholinesterase (ACHE) activity in amniotic fluid is associated with open neural tube defects. The ACHE assay appears to be useful in assessing the evaluation of a positive AFP result in suspected fetal neural tube defects and in evaluating normal anmiotic fluid samples with elevated AFP concentrations. There is indication that the ACHE assay exhibits fewer false positives than the AFP assay. The two assays together are complementary in the clinical assessment of neural tube defects.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
