| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Chromosome Analysis, Amniotic Fluid
Test Code14590
CPT Codes
88235, 88267, 88280
Physician Attestation of Informed Consent
This germline genetic test requires physician attestation that patient consent has been received if ordering medical facility is located in AK, DE, FL, GA, IA, MA, MN, NV, NJ, NY, OR, SD or VT or test is performed in MA.
Preferred Specimen
20 mL amniotic fluid collected in a sterile, screw-cap container
Minimum Volume
5 mL
Instructions
30 mL is preferred if other testing, e.g. microarray, FISH is ordered.
Ship at room temperature. Do not Freeze.
Send all tubes to lab (supernatant for AFP will be split by cytogenetics lab).
Please contact the laboratory Genetic Counselor at 1-866-GENEINFO (1-866-436-3463) with any questions.
Transport Container
Sterile screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Methodology
Culture • Karyotype • Microscopy
Setup Schedule
Mon-Sat
Report Available
11-15 days
Clinical Significance
This test will detect chromosome abnormalities of the fetus including numerical, structural, and mosaic abnormalities. Chromosome analysis will also reveal fetal sex and sex chromosome abnormalities. Indications for prenatal chromosome analysis may include advanced maternal age, abnormal fetal ultrasound, abnormal maternal serum screen, abnormal cell-free DNA results, history of a previous child with a chromosome abnormality, or a parent who carries a balanced chromosomal rearrangement or has another chromosome abnormality.
Performing Laboratory
| Quest Diagnostics Nichols Institute-Chantilly VA |
| 14225 Newbrook Drive |
| Chantilly, VA 20151-2228 |
