| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
VLDL Cholesterol
Test Code319
CPT Codes
84478
Includes
Triglycerides and VLDL-Calculation
Preferred Specimen
1 mL serum
Patient Preparation
Patient should fast 9-12 hours prior to collection
Minimum Volume
0.5 mL
Other Acceptable Specimens
Sodium heparin (green-top) tube • Lithium heparin (green-top) tube
Transport Container
Serum separator tube (SST)
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Anticoagulants other than heparin
Methodology
Spectrophotometry (SP)
Reference Range
| Triglycerides | |||
| ≤9 Years | <75 mg/dL | ||
| 10-19 Years | <90 mg/dL | ||
| ≥20 Years | <150 mg/dL | ||
| Cholesterol, VLDL | <30 mg/dL (calc) |
Clinical Significance
This test measures the serum concentration of triglycerides and provides a calculated value for serum very low-density lipoprotein cholesterol (VLDL-C), which may be used to help assess cardiovascular disease (CVD)-related risk. VLDL is a carrier of serum cholesterol and the main carrier of triglycerides. Often, the VLDL-C test is ordered as part of a lipid profile to provide insight into overall CVD-related risk [1,2].
Triglyceride testing is useful in classification of various lipoprotein disorders and aids in the assessment of risk factors for atherosclerosis, coronary heart disease, and metabolic syndrome. VLDL-C consists of triglyceride-rich lipoprotein particles. Upon entering the circulation, these particles are metabolized to intermediate-density lipoprotein cholesterol (IDL-C) and subsequently low-density lipoprotein cholesterol (LDL-C), a key factor in the pathogenesis of atherosclerosis and coronary heart disease [1,2].
The results of this test should be interpreted in the context of pertinent clinical and family history as well as physical examination findings.
References
1. Grundy SM, et al. Circulation. 2019;139(25):e1082-e1143.
2. Hilbert T, et al. Lipids and dyslipoproteinemia. In: McPherson RA, et al, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. Saunders Elsevier; 2017:226-248.
Triglyceride testing is useful in classification of various lipoprotein disorders and aids in the assessment of risk factors for atherosclerosis, coronary heart disease, and metabolic syndrome. VLDL-C consists of triglyceride-rich lipoprotein particles. Upon entering the circulation, these particles are metabolized to intermediate-density lipoprotein cholesterol (IDL-C) and subsequently low-density lipoprotein cholesterol (LDL-C), a key factor in the pathogenesis of atherosclerosis and coronary heart disease [1,2].
The results of this test should be interpreted in the context of pertinent clinical and family history as well as physical examination findings.
References
1. Grundy SM, et al. Circulation. 2019;139(25):e1082-e1143.
2. Hilbert T, et al. Lipids and dyslipoproteinemia. In: McPherson RA, et al, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. Saunders Elsevier; 2017:226-248.
Performing Laboratory
| Quest Diagnostics-Pittsburgh Lab |
| 875 Greentree Road |
| Pittsburgh, PA 15220-3508 |
