HEPARIN Anti-XA

Test Code
LAB6201


CPT Codes
85520

Preferred Specimen
3.2% Sodium Citrate light blue tube


Minimum Volume
2.7 mL


Instructions
1.(1) FULL, light blue-top (3.2  citrate) tube. 2. Draw and discard a tube prior to light-blue (citrate) tube.


Transport Container
3.2% Sodium Citrate light blue tube


Transport Temperature
Refrigerate specimen


Methodology
Mechanical Clot Detection

Setup Schedule
Set up daily; available 1 day


Reference Range
Low Molecular Weight Heparin (LMWH): Enoxaparin (Lovenox) 
(Target Anti-Xa levels measured 4 hours after dosing after 3rd or 4th dose) 
 
Low Molecular Weight Heparin Therapeutic Ranges (Full anticoagulation): 
Therapeutic twice a day dosing or renally adjusted once a day dosing: 0.6-1.0 IU/mL 
 
Therapeutic once a day dosing: 1.0-2.0 IU/mL 
 
Low Molecular Weight Heparin Thrombosis Prophylaxis (Thromboprophylaxis) Range: 
0.2-0.5 IU/mL (Note: Range is for both once a day and twice a day dosing) 
 
Unfractionated Heparin (UFH) 
(Target anti-Xa levels measured 6 hours after initiation or dose adjustment) 
 
Unfractionated Heparin Therapeutic Ranges: 
 
Venous Thrombosis or Pulmonary Embolism: 0.30-0.70 IU/mL 
 
(For patients with venous thrombosis or pulmonary embolism requiring full intensity heparin anticoagulation.  Therapeutic range correlates to GBMC heparin protocols: Acute Thrombosis Treatment and Atrial Fibrillation/Peri-operative Bridging.) 
 
Moderate Intensity Heparin Anticoagulation: 0.14-0.34 IU/mL 
 
(For patients requiring moderate intensity heparin anticoagulation.  The GBMC Pharmacy and Therapeutics Committee recommends a lower therapeutic range for cardiac patients with acute coronary syndrome, vascular surgery patients and patients requiring heparin for continuous renal replacement therapy.  Therapeutic range correlates to GBMC heparin protocols: Acute Coronary Syndrome, Vascular Post-Operative and Continuous Renal Replacement Therapy.) 


Performing Laboratory
GBMC Hematology



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.