A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

ROS1 FISH

Message
Probes: ROS1 (6q22.1)
Disease(s): Non-small cell lung carcinoma (NSCLC)


Test Code
LAB4119


CPT Codes
88377x1 manual or 88374x1 automated.

Preferred Specimen
Paraffin Block: Send paraffin block. Also send circled H&E slide for tech-only (required).


Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.


Methodology
FISH

Report Available
3-5 days


Clinical Significance
ROS1 gene rearrangements are found in 1-2% of non-small cell lung carcinoma (NSCLC). Pre-clinical and early clinical evidence suggests ROS1-rearranged tumors may be sensitive to the dual ALK/MET inhibitor crizotinib.


Performing Laboratory
Neogenomics Laboratories



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.