BCR/ABL1/ASS1 t(9;22)

Message
Probes: ABL1 (9q34); ASS1 (9q34; BCR (22q11.2)
Disease(s): CML, ALL, MPN
Note: For suspected ALL, STAT processing is available by request. Note STAT along with MD contact name and phone number to receive STAT results.


Test Code
LAB6065


Alias/See Also
Philadelphia chromosome, Philadelphia translocation


CPT Codes
88374x1 automated. Codes may differ if manual analysis is performed.

Preferred Specimen
Bone Marrow Aspirate: 1-2mL Sodium Heparin Tube. EDTA tube is acceptable
•Peripheral Blood: 2-5mL Sodium Heparin Tube. EDTA tube is acceptable
•Fresh, Unfixed Tissue: Tissue in RPMI
•Fluids: Equal parts RPMI to specimen volume.
•Paraffin or Cut Slides: N/A


Instructions
Refrigerate specimen. Do not freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.


Methodology
FISH

Report Available
3-5 days. STAT results, when requested, are reported 12-24 hours from receipt in the NeoGenomics laboratory.


Clinical Significance
Translocation 9;22 is seen in chronic myelogenous leukemia and acute lymphoblastic leukemia.


Performing Laboratory
Neogenomics Laboratories



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.