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AML Panel - Standard
MessageProbes: 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (Cen 7, 7q22, 7q31) | Trisomy 8 (Cen 8) | MLL (11q23) | 20q- (20q12, 20qter) | RUNX1/RUNX1T1 (ETO/AML1) t(8;21) | PML/RARA t(15;17) | CBFB inv(16), t(16;16)
Probes may be ordered separately except +8 and 20q- which are combined.
Disease(s): Acute myeloid leukemia Probes may be ordered separately except +8 and 20q- which are combined.
Probes may be ordered separately except +8 and 20q- which are combined.
Disease(s): Acute myeloid leukemia Probes may be ordered separately except +8 and 20q- which are combined.
Test Code
LAB4094
Alias/See Also
Acute myeloid leukemia
CPT Codes
88374x7 automated. Codes may differ if manual analysis is performed.
Preferred Specimen
•Bone Marrow Aspirate: 1-2 mL sodium heparin tube. EDTA tube is acceptable.
•Peripheral Blood: 2-5 mL sodium heparin tube. EDTA tube is acceptable.
•Fresh, Unfixed Tissue: Tissue in RPMI.
•Fluids: Equal parts RPMI to specimen volume.
•Paraffin Block or Cut Slides: Not available.
•Peripheral Blood: 2-5 mL sodium heparin tube. EDTA tube is acceptable.
•Fresh, Unfixed Tissue: Tissue in RPMI.
•Fluids: Equal parts RPMI to specimen volume.
•Paraffin Block or Cut Slides: Not available.
Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.
Methodology
FISH
Report Available
3-5 days. STAT results for PML-RARA, when requested, are reported 12-24 hours from receipt in the NeoGenomics laboratory
Clinical Significance
| The AML Standard FISH Panel identifies the most frequent cytogenetic abnormalities associated with favorable, intermediate, and poor risk |
Performing Laboratory
Neogenomics Laboratories
