PRO- BNP

Test Code

LAB106

Alias/See Also

BRAIN NATRIURETIC PEPTIDE, BNP
NT-proBNP

CPT Codes
83880

Preferred Specimen

Green Top/Gel LiHep

Minimum Volume

2.0 mL

Methodology
ECLIA

Setup Schedule

Set Up:DAILY Report Available:1 DAY

Reference Range

ProBNP
0-75yrs: <=125 pg/mL
>75yrs: <=450 pg/mL

Clinical Significance

B-Type natriuretic peptide (BNP) is a cardiac neurohormone secreted from the cardiac ventricles as a response to ventricular volume expansion and pressure overload. BNP serum and plasma levels, as well as concentrations of the biologically inactive prohormone, proBNP, are elevated in patients with left ventricular dysfunction and correlate with the New York Heart Association (NYHA) class and prognosis. When used with the appropriate cut-off values, proBNP assay yields negative predictive values ranging from 97.8% to 100.0% depending on age and gender. THRESHOLD VALUE: < 75 years of age 125 pg/mL >= 75 years of age 450 pg/mL Patient values exceeding the age-specific threshold values described above may be indicative of CHF.

Performing Laboratory
GBMC Chemistry

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.