LITHIUM

Test Code

LAB29

CPT Codes
80178

Preferred Specimen

7 mL Red Top Tube

Minimum Volume

1.0 mL

Transport Temperature

Refrigerate

Methodology
Colorimetric

Setup Schedule

Set Up:Daily Report Available:1 day

Reference Range

Therapeutic: 0.6 - 1.2 mmol/L
Critical value: >1.5 mmol/L

Clinical Significance

Lithium, administered as lithium carbonate, is used for the treatment of the manic phase of affective disorder, mania and manic-depressive illness. It acts by enhancing reuptake of neurotransmitters, thereby decreasing their concentration in the neuronal junction. This produces a sedating effect on the central nervous system. Absorption of lithium from the gastrointestinal tract is complete, with peak plasma concentration reached from 2 to 4 hours after an oral dose. Clearance is predominately a function of the kidneys, where active reabsorption occurs. Early symptoms of lithium intoxication include apathy, sluggishness, drowsiness, lethargy, speech difficulty, irregular tremors, myoclonic twitchings, muscle weakness and ataxia.

Performing Laboratory
GBMC Chemistry

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.