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OSMOLALITY, 24 HOUR URINE
Test CodeLAB420
CPT Codes
81050, 83935
Preferred Specimen
Urine, 24hour
Minimum Volume
0.2 mL
Instructions
TO COLLECT A 24-HOUR URINE SPECIMEN: At the hour selected to start the 24-hour period, have the patient urinate and discard. From that time collect all urine passed in a clean container and transfer immediately to this bottle. DO NOT HAVE PATIENT URINATE DIRECTLY INTO THE BOTTLE. Have the patient pass the last urine at the end of the 24-hour period and add this into the bottle. The container must be kept refrigerated at all times during the 24-hour collection.See Collection Notes below.
Transport Container
24 hour urine container, NO preservative
Transport Temperature
Refrigerated
Methodology
Freezing Point Depression
Setup Schedule
Set Up:Monday thru Friday 10 AM cut off time Report Available:1 day
Reference Range
| Osmolality 24 hr Urine | mOsm/kg | 300-900 |
Clinical Significance
Osmolality measurements in urine are used in assessing the concentrating ability of the kidneys, since regulation of water excretion is, in part, determined by the osmolality of the fluid compartments of the body. In chronic progressive renal failure, the concentrating ability of the tubules is diminished, which may be demonstrated with a urine osmolality measurement. In polyuria due to diabetes insipidus, the urine osmolality is very low, and this may be used to differentiate this condition from polyuria of neurogenic origin.
Performing Laboratory
GBMC Hematology
