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BCR-ABL1 Standard p210, p190
MessageReal-time RT-PCR for quantitative detection of t(9;22) BCR-ABL1 fusion transcripts that result in major p210 (E13, E14) or minor p190 (E1) fusion proteins with option to add p230 detection (micro or atypical variant). p230 testing may be ordered as a stand-alone test. For p210 and p190, analytical sensitivity is 1 tumor cell in 100,000 normal cells, log reduction score and percent abnormal are reported, and longitudinal data will appear as a NeoTRACK Result on the report. For p230, results are reported as percent abnormal. Testing is New York approved for p210 and p190 only.
Test Code
LAB4651
Alias/See Also
Philadelphia chromosome, BCR-ABL1 Major, BCR-ABL1 Minor, BCR/ABL1 Standard
CPT Codes
81479x1, add 81208x1 if p230 testing is performed
Preferred Specimen
Bone Marrow: 2 mL EDTA tube
Peripheral Blood: 5 mL EDTA tube
Peripheral Blood: 5 mL EDTA tube
Transport Temperature
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Ship same day as drawn whenever possible; specimens <72 hours old preferred.
Specimen Stability
Ship same day as drawn whenever possible; specimens <72 hours old preferred.
Methodology
Molecular
Report Available
7 days
Clinical Significance
Useful for diagnosis and monitoring of Philadelphia chromosome-positive cases of CML and ALL.
Performing Laboratory
Neogenomics Laboratories
