IMMUNOGLOBULIN IGA

Test Code

LAB73

CPT Codes
82784

Preferred Specimen

5.0 mL Gold SST

Minimum Volume

2.0 mL

Other Acceptable Specimens

7 mL Red Top Tube

Transport Container

SST

Transport Temperature

Refrigerate specimen

Methodology
Immunoturbidimetric

Setup Schedule

Set Up:Daily Report Available:Same day

Reference Range

Age (Female/Male)	Reference Range
<1M	1.3-53 mg/dL
1M-2M	2.8-47.2 mg/dL
2M-3M	4.6-46.0 mg/dL
3M-6M	8.1-68.6 mg/dL
6m-2Y	14.0-123.0 mg/dL
2Y-3Y	22.0-159.0 mg/dL
3Y-8Y	22.0-202.0 mg/dL
8Y-10Y	45.0-236.0 mg/dL
>10Y	88.0-411.0 mg/dL

Clinical Significance

IgA accounts for 13% of the total immunoglobulins and serves to protect the skin and mucosa against microorganisms. It is capable of binding toxins, and in combination with lysozyme develops antibacterial and antiviral activity. IgA is the predominant immunoglobulin in body secretions, such as colostrum, saliva, and sweat. Secretory IgA provides defense against local infections and is important in processing food antigens in the gut. In serum, IgA exists in monomeric and polymeric forms. Increased polyclonal IgA levels may occur in chronic liver diseases, chronic infections, autoimmune disorders (rheumatoid arthritis, systemic lupus erythematosis), sarcoidosis, and Wiskott-Aldrich syndrome.2-5 Monoclonal IgA increases in IgA myeloma. Decreased synthesis of IgA is observed in acquired and congenital immunodeficiency diseases such as Bruton type agammaglobulinemia. Increased loss of IgA is caused by protein-losing gastroenteropathies and loss through skin from burns.

Performing Laboratory
GBMC Chemistry

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.