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Vancomycin, Trough
MessageDraw blood 0-60 minutes prior to next dose.
Test Code
LAB39
Alias/See Also
Vanc, Pre
CPT Codes
80202
Preferred Specimen
7 ml Red Top Tube
Minimum Volume
2.0 mL
Instructions
Preferred: Patient in steady state Collect 1 hour prior to administration 1 plain, red-top tube drawn 0-60 minutes prior to next dose.
Transport Temperature
Refrigerate
Methodology
KIMS
Setup Schedule
Set Up:Daily Report Available:same day
Reference Range
10 - 20 ug/mL Critical: >22 ug/mL |
Clinical Significance
Vancomycin is a glycopeptide antibiotic which is bactericidal against many gram-positive and some gram-negative cocci. It is useful in therapy of severe staphylococcal (including methicillin-resistant staphylococci) infections in patients who cannot receive or who have failed to respond to the penicillins and cephalosporins. Vancomycin HCI has been used successfully alone in the treatment of staphylococcal (including methicillin-resistant staphylococci) endocarditis. Because of its ototoxicity, vancomycin should be used with care in patients with renal insufficiency. Concurrent and sequential use of other neurotoxic and/or nephrotoxic antibiotics, particularly streptomycin, neomycin, kanamycin, gentamicin, cephaloridine, paramomyfin, viomycin, polymyxin.
Performing Laboratory
GBMC Chemistry