ACTIVATED PTT

Test Code

LAB325

Alias/See Also

PTT, APTT, ACTIVATED PARTIAL THROMBOPLASTIN

CPT Codes
85730

Preferred Specimen

3.2% Sodium Citrate light blue tube

Minimum Volume

2.7 mL

Instructions

1.(1) FULL, light blue-top (3.2 citrate) tube. 2. Draw and discard a tube prior collecting the light-blue (citrate) tube.

Transport Container

3.2% Sodium Citrate light blue tube

Transport Temperature

Refrigerated

Methodology
Mechanical Clot Detection

Setup Schedule

Set Up:Daily Report Available:Routine 4 hours / STAT 1 hour

Reference Range

PARTIAL THROMBOPLASTIN

seconds

23.4 - 34.9 Critical values: > 105.9

Clinical Significance

The Activated Partial Thromboplastin Time test is used to monitor deficiencies or changes in the intrinsic pathway of coagulation. Extracted cephalins are used as a source of phospholipids to replace the platelet factor3 released during coagulation in vivo. Particulate activators enhance the activation of the contact factors of the intrinsic pathway: Factors XII, XI, high molecular weight kininogen (HMWK), and prekallikrein (PK). The APTT is used to test all factors of the intrinsic and common pathways, including factors, I, II, V, VIII, IX, X and the contact factors. In addition, it is sensitive to certain inhibitors of coagulation such as heparin, lupus anticoagulant, and specific factor inhibitors. The Activated Partial Thomboplastin Time is the most commonly used test to monitor heparin therapy.

Performing Laboratory
GBMC Hematology

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.