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p27, IHC without Interpretation
Test Code90226
CPT Codes
88342
Preferred Specimen
1 formalin fixed paraffin block
Minimum Volume
1 block
Other Acceptable Specimens
3 Slides Unstained, positively charged slides IHC Specimen Transport Kit
Instructions
Please include surgical pathology report.
Transport Container
IHC Specimen Transport Kit
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Do Not Freeze
Refrigerated: Indefinitely
Frozen: Do Not Freeze
Methodology
Immunohistochemistry
Setup Schedule
Set up: Mon-Fri Morning; Report available: Next day
Clinical Significance
Dysregulation of the nuclear cycle regulator p27 is
implicated in the development and progression of oral
squamous cell carcinoma (including by HPV).
Underexpression of p27 is an adverse prognostic marker in
breast, lung, prostate, and thyroid carcinomas. It is
also deleted/underexpressed in some high-grade
hematopoietic tumors.
implicated in the development and progression of oral
squamous cell carcinoma (including by HPV).
Underexpression of p27 is an adverse prognostic marker in
breast, lung, prostate, and thyroid carcinomas. It is
also deleted/underexpressed in some high-grade
hematopoietic tumors.
