A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

COX-2, IHC with Interpretation

Test Code
90157


CPT Codes
88342

Preferred Specimen
Formalin-fixed paraffin-embedded tissue block submitted in an IHC Specimen Transport kit


Minimum Volume
3 slides


Other Acceptable Specimens
5 slides unstained, positively charged slides


Instructions
Please include surgical pathology report


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Methodology
Immunohistochemistry

Setup Schedule
Set up: Mon-Sat; reports: 2-4 days


Reference Range
See Laboratory Report


Clinical Significance
Tissue cycloxgenase (COX) 2 is an enzyme expressed in the cytoplasm of many cells types. COX2 overexpression has been associated with adverse prognosis in carcinomas of the colon, breast, pancreas, and adenocarcinoma of the lung. Its activity, but not its expression level, is inhibited by nonsteroidal anti-inflammatory agents.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.