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CD35, IHC without Interpetation [40041X]
Test Code40041
CPT Codes
88342
Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block
Other Acceptable Specimens
Minimum: 3 unstained, positively charged slides
Transport Container
IHC Specimen Transport Kit
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable
Refrigerated: Indefinitely
Frozen: Unacceptable
Methodology
Immunohistochemistry (IHC)
Setup Schedule
Set up: Mon-Fri a.m.; Report available: Next day
Clinical Significance
CD35 is a complement binding protein that is strongly expressed in normal and neoplastic follicular dendritic cells and weakly expressed in some lymphocytes. Its primary use in immunohistochemistry is to identify tumors of follicular dendritic cell type and is therefore often included in diagnostic panels for undifferentiated epithelioid and spindle cell neoplasms.
