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Prothrombin Time with INR
Test Code10144
CPT Codes
85610<br /> Limited Access Code
Preferred Specimen
1 mL platelet-poor plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
0.5 mL plasma • 4.1 citrate whole blood • 2.4 mL pediatric citrate whole blood
Other Acceptable Specimens
5 mL random citrated whole blood collected in a 3.2% sodium citrate (light blue-top) tube • 2.7 mL random pediatric citrated whole blood collected in a 3.2% sodium citrate (light blue-top) tube
Instructions
A completely filled tube is necessary because the correct ratio of blood to citrate is critical (9:1). Mix by gentle inversion 3-4 times. Do not uncap.
Transport Temperature
Plasma: Frozen
Whole blood: Room temperature
Whole blood: Room temperature
Specimen Stability
Plasma
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 14 days
Whole blood
Room temperature: 48 hours
Refrigerated: Unacceptable
Frozen: Unacceptable
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 14 days
Whole blood
Room temperature: 48 hours
Refrigerated: Unacceptable
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Improper blood to citrate ratio • High hematocrit • Improper blood collection
Methodology
Photo-optical Clot Detection
Setup Schedule
Set up: Mon-Sat; Report available: 1-3 days
Reference Range
See Laboratory Report
Clinical Significance
This is a screening test for abnormalities of coagulation factors that are involved in the extrinsic pathway. Test is also used to monitor effects of Warfarin therapy and to study patients with hereditary and acquired clotting disorders.
