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PTT Mixing Study added to PTT
MessageSpecimen must be less than 12 hours old.
Test Code
LAB6118
Includes
Partial thromboplastin time (Patient Plasma) in seconds, Partial thromboplastin time (Patient Plasma plus Normal Plasma) in seconds
Instructions
"Routine venipuncture; Collect one 2.7ml Blue top (sodium citrate) 90% of tube must be filled. do not use syringe for collection."
Specimen Stability
Room temperature, stable 12 hours.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Tube <90% full; visible hemolysis; clotted specimen; improperly labeled specimen.
Specimen greater than 12 hours old.
Specimen greater than 12 hours old.
Reference Range
"APTT: 24.1-37.4 seconds ;
Critical: Greater than 45.1 Seconds
Normal Cal Plasma: 24.0-36.0 seconds
1:1 Patient Plasma/Normal Cal Plasma: See interpretive data"
Critical: Greater than 45.1 Seconds
Normal Cal Plasma: 24.0-36.0 seconds
1:1 Patient Plasma/Normal Cal Plasma: See interpretive data"
Clinical Significance
"A correction of the patient PTT with the addition of normal plasma to within normal range is indicative of a factor VIII, IX, X, XI or XIII deficiency. A patient with a factor deficiency may have a bleeding tendancy. A partial correction of the patient PTT (within <5 sec), no correction or a longer PTT result is indicative of a lupus like inhibitor. A patient with an inhibitor can be at risk for thrombotic episodes. The presence of anticoagulant drugs such as heparin or direct thrombin inhibitors cannot be excluded."