PTT Mixing Study added to PTT

Message
Specimen must be less than 12 hours old.


Test Code
LAB6118


Includes
Partial thromboplastin time (Patient Plasma) in seconds, Partial thromboplastin time (Patient Plasma plus Normal Plasma) in seconds


Instructions
"Routine venipuncture; Collect one 2.7ml Blue top (sodium citrate) 90% of tube must be filled.  do not use syringe for collection."


Specimen Stability
Room temperature, stable 12 hours.


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Tube <90% full; visible hemolysis; clotted specimen; improperly labeled specimen.
Specimen greater than 12 hours old.


Reference Range
"APTT: 24.1-37.4 seconds ;
Critical: Greater than 45.1 Seconds
Normal Cal Plasma: 24.0-36.0 seconds
1:1 Patient Plasma/Normal Cal Plasma: See interpretive data"


Clinical Significance
"A correction of the patient PTT with the addition of normal plasma to within normal range is indicative of a factor VIII, IX, X, XI or XIII deficiency.  A patient with a factor deficiency may have a bleeding tendancy. A partial correction of the patient PTT (within <5 sec), no correction or a longer PTT result is indicative of a lupus like inhibitor.  A patient with an inhibitor can be at risk for thrombotic episodes. The presence of anticoagulant drugs such as heparin or direct thrombin inhibitors cannot be excluded."




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.