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Erythropoietin (EPO)
Test CodeLAB873
Quest Code
427
Alias/See Also
EPO
ERYTH
ERYTH
CPT Codes
82668
Preferred Specimen
1 mL serum
Patient Preparation
Due to diurnal variation, it is recommended that specimens be collected between 7:30 am and noon
Minimum Volume
0.5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 10 days
Refrigerated: 18 days
Frozen: 28 days
Refrigerated: 18 days
Frozen: 28 days
Methodology
Immunoassay (IA)
Setup Schedule
A.M. Sets up 3 days a week.
Report Available
Reports in 2 days.
Reference Range
Male (mIU/mL) | Female (mIU/mL) | |
<1 Year | Not established | Not established |
1-3 Years | 1.7-17.9 | 2.1-15.9 |
4-6 Years | 3.5-21.9 | 2.9-8.5 |
7-9 Years | 1.0-13.5 | 2.1-8.2 |
10-12 Years | 1.0-14.0 | 1.1-9.1 |
13-15 Years | 2.2-14.4 | 3.8-20.5 |
16-18 Years | 1.5-15.2 | 2.0-14.2 |
>18 Years | 2.6-18.5 | 2.6-18.5 |
Clinical Significance
Elevated levels of serum erythropoietin (EPO) occur in patients with anemias due to increased red cell destruction in hemolytic anemia and also in secondary polycythemias associated with impaired oxygen delivery to the tissues, impaired pulmonary oxygen exchange, abnormal hemoglobins with increased oxygen affinity, constriction of the renal vasculature, and inappropriate EPO secretion caused by certain renal and extrarenal tumors. Normal or depressed levels may occur in anemias due to increased oxygen delivery to tissues, in hypophosphatemia, and in polycythemia vera.
Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130