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Sed Rate, Automated
Test CodeLAB322
Alias/See Also
ESR; Westergren Sed Rate; Sedimentation Rate
CPT Codes
85652
Instructions
"Routine venipuncture
Collect one 4.0ml Lavender top (EDTA) tube"
Collect one 4.0ml Lavender top (EDTA) tube"
Specimen Stability
Room temperature, stable 12 hours.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis; gross lipemia; insufficient quantity; clotted specimen; improperly labeled specimen
Methodology
Streck ESR-Auto Plus
Setup Schedule
Daily
Report Available
Within 24 hours
Reference Range
"Female: 0-17 mm/hour
Male: 0-14 mm/hour"
Male: 0-14 mm/hour"
Clinical Significance
"The ESR test measures the settling of erythrocytes in diluted human plasma over a specified time period. The ESR is directly proportional to the RBC mass and inversely proportional to plasma viscosity.
In normal whole blood, RBCs do not form rouleaux (stacking in long chains); the RBC mass is small and therefore the ESR is decreased. In abnormal conditions when RBCs can form rouleaux, the RBC mass is greater, thus increasing the ESR.
ESR is increased in conditions with elevated fibrinogen or immunoglobulin levels. The sed rate is decreased in conditions when microcytes, sickle cells, and spherocytes are present."
In normal whole blood, RBCs do not form rouleaux (stacking in long chains); the RBC mass is small and therefore the ESR is decreased. In abnormal conditions when RBCs can form rouleaux, the RBC mass is greater, thus increasing the ESR.
ESR is increased in conditions with elevated fibrinogen or immunoglobulin levels. The sed rate is decreased in conditions when microcytes, sickle cells, and spherocytes are present."
