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Lactic Acid
MessageMUST BE DRAWN AT MAIN LAB CHOMP
Test Code
LAB95
Alias/See Also
LA, LAC
CPT Codes
83605
Instructions
Routine venipuncture. Collect one Gray top (K Oxalate and NA fluoride). Place specimen on ice. Spin specimen and separate plasma from cells WITHIN 15 MINUTES.
Specimen Stability
Plasma stable refrigerated for 3 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Failure to follow proper collection and handling procedures
Methodology
Colorimetric: Lactate in the sample is oxidized by lactate oxidase to pyruvate and hydrogen peroxide.
Setup Schedule
Daily STAT
Report Available
Daily 4 hours; STAT: 1hr
Reference Range
0.7-2.1 mmol/L
Clinical Significance
Lactate is the end product of the anaerobic metabolism of glucose. The concentration of lactate in the blood is dependent on the rate of production in muscle cells and erythrocytes and the rate of metabolism in the liver. Lactic acidosis usually results from overproduction or underutilization of lactate. Elevated lactate levels can occur as a result of tissue hypoxia; diabetes mellitus; phenformin therapy; malignancies; glycogen storage disease; ethanol, methanol, or salicylate ingestion; and metabolic acidosis.