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Ferritin
Test CodeLAB68
CPT Codes
82728
Instructions
"Routine venipuncture
Collect one 5ml Red/gold top serum separator tube"
Collect one 5ml Red/gold top serum separator tube"
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis or lipemia; failure to follow proper collection or storage procedures
Methodology
Immunometric:The amount of HRP conjugate bound is directly proportional to the concentration of ferritin present
Setup Schedule
Daily/STAT
Report Available
within 24 Hours
Reference Range
"Female, Age 0-50: 6.24-137.0 ng/mL
Female, Age greater than 50: 11.0-264.0 ng/mL
Male, Age any: 17.9-464.0 ng/mL"
Female, Age greater than 50: 11.0-264.0 ng/mL
Male, Age any: 17.9-464.0 ng/mL"
Clinical Significance
Ferritin plays a significant role in the absorption, storage, and release of iron. The storage form of iron ferritin remains in the body tissues until it is needed for erythropoiesis. When needed, the iron molecules are released from the apoferritin shell and bound to transferrin, the circulating plasma protein that transports iron to the erythropoietic cells. Ferritin is found in serum in low concentrations and is directly proportional to the body's iron stores. Serum ferritin concentration, when analyzed with other factors such as serum iron, iron-binding capacity, and tissue iron stores, is valuable in the diagnosis of iron deficiency anemias, anemias of chronic infection, and conditions such as thalassemia and hemochromatosis that are associated with iron overload. Measurement of serum ferritin is particularly valuable in distinguishing iron deficiency anemias caused by low iron stores from those resulting from inadequate iron utilization.
Additional Information
NCD-ABN Serum Iron Studies-Ferritin
