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DIGOX; Digoxin
Test CodeLAB23
CPT Codes
80162
Preferred Specimen
" Routine venipuncture Collect one 5ml Red/gold top serum separator tube. "
Instructions
Specimens should be drawn at least six to eight hours after the last dose. If toxicity is suspected, specimens may be drawn at any time.
Specimen Stability
Refrigerate, stable 48 hours; stable 8 hours at room temperature
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, lipemia, or icterus; failure to follow stability requirements
Methodology
"Multiple-point immuno-rate: The rate of dye formation is inversely propotional to the digoxin conc. in the sample."
Setup Schedule
Daily
Report Available
Within 48 hours
Reference Range
"
0.8-2.0 ng/mL
Critical High Value: >3.1 ng/mL
"
0.8-2.0 ng/mL
Critical High Value: >3.1 ng/mL
"
Clinical Significance
"Digoxin is administered for conditions of heart failure or in the treatment of certain cardiac arrhythmias. Digoxin therapy is monitored for possible toxicity and inadequate therapeutic response. The presence of therapeutic antidigoxin immune fragments
in the specimen may result in spuriously high digoxin levels."
in the specimen may result in spuriously high digoxin levels."
Additional Information
NCD-ABN Digoxin Theraputic Assay
