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Acetone
Test CodeLAB456
Alias/See Also
Ketones
CPT Codes
82009
Preferred Specimen
Heparanized plasma
Centriguge within 2 hours of collection
Centriguge within 2 hours of collection
Minimum Volume
1 mL
Other Acceptable Specimens
Serum (SST)
Instructions
Routine venipuncture. 5ml LtGreen/Mint top lithium heparin tube or SST.
Transport Temperature
Refrigerated (2-8C)
Specimen Stability
Refrigerated 3 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Insufficient quantity; failure to follow stability requirements
Methodology
Nitroprusside method
Setup Schedule
Daily
Report Available
Within 4 hours
STAT 60 minutes
STAT 60 minutes
Limitations
If acute acetaminophen toxicity is suspected, correlation of levels with hours after ingestion is required for interpretation (using the Rumack-Matthew nomogram). In general, a value of 200 ug/ml within 4 hours of ingestion or >50 ug/ml at 12 hours predicts severe liver damage, and treatment with acetylcysteine is suggested.
Reference Range
Negative
Abnormal: Small, Moderate, Large
Abnormal: Small, Moderate, Large
Clinical Significance
The presence of acetone may indicate exposure to acetone; it is also a metabolite of isopropanol and may be detected during ketoacidosis.
Performing Laboratory
CH CHOMP HOSPITAL LAB (831-625-4811): CH CHEMISTRY