| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Parietal Cell Antibody, ELISA
Test CodeLAB514
Quest Code
15114
Alias/See Also
PCA, GPCA
CPT Codes
83516
Preferred Specimen
1 mL serum
Minimum Volume
0.3 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 8 hours
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia
Methodology
Immunoassay (IA)
Setup Schedule
A.M. Sets up 3 days a week.
Reference Range
| ≤20.0 U | Negative | |
| 20.1-24.9 U | Equivocal | |
| ≥25.0 U | Positive | |
Clinical Significance
Gastric Parietal Cell Antibodies are found in 90% of patients with pernicious anemia. They are also found in autoimmune chronic atrophic gastritis preceding pernicious anemia. The antigenic target is the H+/K+ ATPase gastric proton pump responsible for parietal cell acid generation in the stomach.
Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130
