Alpha-1-Antitrypsin Quantitation

Test Code

LAB810

Quest Code

235

Alias/See Also

A1ATR; A1AT

CPT Codes
82103

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Instructions

Allow blood to clot in the original closed container at room temperature (usually 20 to 30 minutes). After clot has formed, centrifuge blood 10 minutes at a relative centrifugal force (CRF) of 850 to 1000 g in the stoppered container.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 90 days

Methodology
Immunoturbidimetric Assay

Setup Schedule

Set up: Tues, Thurs, Sat; Report available: 2-4 days

Reference Range

83-199 mg/dL

Clinical Significance

Alpha-1-Antitrypsin level may be increased in normal pregnancy and in several diseases including chronic pulmonary disease; hereditary angioedema; renal, gastric, liver and pancreatic diseases; diabetes; carcinomas and rheumatoid diseases. Alpha-1-Antitrypsin may be decreased in emphysema, hepatic cirrhosis, respiratory distress syndrome of the newborn, nephrosis, malnutrition and cachexia. If a deficiency is present, aat phenotyping may be considered to confirm heterozygous versus homozygous deficiencies.

Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.