Myasthenia Gravis Panel 2 with Reflex to MuSK Antibody

Test Code

LAB93859

Quest Code

93859

CPT Codes
83519 (x3)

Includes

Acetylcholine Receptor Blocking Antibody
Acetylcholine Receptor Binding Antibody
Acetylcholine Receptor Modulating Antibody

If AChR blocking is <15% of inhibition, AChR binding is ≤0.30 nmol/L, and AChR modulating is <32% binding inhibition, then MuSK Antibody Test will be performed at an additional charge (CPT code(s) 86366).

Preferred Specimen

3 mL serum

Minimum Volume

0.7 mL

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Lipemia • Microbially contaminated

Methodology
Immunoassay (IA)

FDA Status
*This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Report available: 7 days

Reference Range

See Laboratory Report

Clinical Significance

Myasthenia gravis (MG) is an autoimmune disorder affecting the neuromuscular junction. 80% of patients with generalized MG have serum antibodies to AChR - Blocking, Binding, or Modulating. Antibodies to MuSK make up a variable proportion of the remaining 20%.

Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.