CYTOPATHOLOGY, GYN, +/- High Risk HPV

Message
ALL PATHOLOGY SPECIMENS MUST BE SUBMITTED WITH A PRINTED COPY OF THE ORDER


Test Code
LAB4


CPT Codes
88141- MD Review, 88175

Includes
Cytological evaluation of a ThinPrep made from cervical scraping, endocervical brushing, vaginal mucosa scraping. Clinician must indicate whether high-risk HPV testing is to be performed per ASCCP guidelines, regardless of diagnosis, reflex if ascus, or not at all. If per guidelines is requested, HPV testing will be performed in cases with a cytologic diagnosis of “ASCUS” in patients 25 and older, and in cases with cytologic diagnosis of “Negative for Intraepithelial Lesion or Malignancy” in patients 30 and older, once per 5 calendar years. Testing algorithm may vary depending on other patient factors such as prior diagnoses or menopausal status. Some non-neoplastic diseases such as Candida species, Trichomonas vaginalis, Actinomyces species and viral cytopathic changes may also be diagnosed.
 
 


Preferred Specimen
PAP THIN PREP: One PreservCyt Solution Vial 


Instructions
Patient should avoid douching forty-eight to seventy-two hours prior to examination. Sample the ectocervix using a plastic spatula. Rinse the spatula into the PreservCyt Solution vial by swirling the spatula vigorously in the vial ten times. Sample the endocervix using an endocervical brush. Rinse the brush in the same vial by rotating the device in the solution ten times while pushing against the PreservCyt vial wall. Swirl the brush vigorously to further release material. Discard the brush and spatula. Securely tighten the 
cap and label the vial with patient's name and hospital number. Include all pertinent history with paper requisition. 
 
For Thin Prep pap smears, the clinician must indicate whether high-risk HPV testing is to be performed per 2012 ASCCP guidelines, regardless of diagnosis, or not at all. More information is available at: www.asccp.org
 
 


Transport Temperature
Ambient


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Unlabeled PreservCyt vial 


Methodology
Manual Slide Review and ThinPrep Imager Duo

Setup Schedule
Monday-Friday, holidays excluded


Clinical Significance
2012 ASCCP guidelines for cervical cancer screening with Pap and HPV tests take into account the patient’s age, cytology result, pregnancy status, post-menopausal status, and cervical cytology and surgical pathology findings within the past few years. Management 
recommendations are given per these guidelines.  
 


Performing Laboratory
West Virginia University Hospital, Inc.
Berkeley Medical Center
Camden Clark Medical Center
United Hospital Center



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.