CREATININE with eGFR

LAB66

Creatinine and estimated glomerular filtration rate (eGFR)

One 4.5 mL Light Green top tube
Pediatric: One light green top microtainer

Dark Green top, Red top,or Gold top tube 

Sample must be centrifuged within two hours of collection. 

Refrigerated

Centrifuge within 2 hours of collection  
Ambient: 7 days   Refrigerated: 7 days   Frozen: 3 months
 

Sunday-Saturday

Age	Sex	Reference Range (mg/dl)
0 days-12 months	Female	0.20-0.45
1-5 years	Female	0.20-0.50
6-10 years	Female	0.25-0.60
11-15 years	Female	0.35-0.85
≥ 16 years	Female	0.60-1.05
0 days- 12 months	Male	0.20-0.45
1-5 years	Male	0.20-0.50
6-10 years	Male	0.25-0.60
11-14 years	Male	0.35-0.85
≥ 15 years	Male	0.75-1.35

Interpretive Information
The eGFR is calculated based on the 2021 CKD-EPI Creatinine Equation:
eGFR = 142 x min(S_Cr/κ, 1)^α x max(S_Cr /κ, 1)^-1.200 x 0.9938^Age x 1.012 [if female]

The eGFR estimates kidney function and is used to determine a patient’s stage of chronic kidney disease based on National Kidney
Foundation guidelines:
    • Stage 1 comprises patients who have kidney damage but a normal eGFR (90 or higher).
    • Stage 2 comprises patients with a mild reduction in eGFR (60 to 89).
    • Stage 3 consists of a moderate eGFR reduction (30 to 59).
    • Stage 4 consists of a severe eGFR reduction (15 to 29).
    • Stage 5 consists of kidney failure, marked by eGFR <15.
In the absence of kidney damage, neither G1 or G2 fulfill criteria for CKD per KDIGO.

Note: For children <18 years old, eGFR is calculated based on the CKiD U25 Creatinine equation; a calculator is
available on the NIDDK website.