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Von Willebrand Factor Activity (Mayo)
Test CodeLAB3562
Alias/See Also
1232900151 / MAYO test code VWACT
CPT Codes
85397
Preferred Specimen
Light-blue top (3.2% sodium citrate)
Minimum Volume
4 mL
Instructions
Collection Instructions: 1. Specimen must be collected prior to factor replacement therapy. 2. For complete instructions, see Coagulation Guidelines for Specimen Handling and Processing. 3. Centrifuge, transfer all plasma into a polypropylene vial, and centrifuge plasma again. 4. Aliquot plasma (1-2 mL per aliquot) into 2 separate polypropylene vials leaving 0.25 mL in the bottom of centrifuged vial. 5. Freeze plasma immediately (no longer than 4 hours after collection) at -20 degrees C or, ideally, < or =-40 degrees C. 6. Send specimens in the same shipping container. Additional Information: 1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results. 2. Each coagulation assay requested should have its own vial.
Transport Temperature
Frozen
Specimen Stability
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross Hemolysis, Lipemia, Icterus.
Reference Range
SEE RESULT REPORT
Performing Laboratory
MAYO CLINIC
Last Updated: August 26, 2026
