Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum

Test Code

3041007017

Alias/See Also

1232900032 / MAYO test code ENS2

CPT Codes
86255 (23) 86341

Preferred Specimen

Red Top

Patient Preparation
1. For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication or intravenous immunoglobulin treatment. 2. This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held 1 week and assayed if sufficiently decayed or canceled if radioactivity remains. 3. Patient should have no general anesthetic or muscle-relaxant drugs in the previous 24 hours.

Minimum Volume

2.5 mL

Other Acceptable Specimens

Gold Top

Instructions

Provide the following information: -Relevant clinical information -Ordering provider name, phone number, mailing address, and e-mail address Patient Preparation: 1. For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication or intravenous immunoglobulin treatment. 2. This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held 1 week and assayed if sufficiently decayed or canceled if radioactivity remains. 3. Patient should have no general anesthetic or muscle-relaxant drugs in the previous 24 hours.

Transport Temperature

Refrigerated

Reference Range

SEE RESULT REPORT

Performing Laboratory
MAYO CLINIC

Last Updated: August 26, 2026

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.