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Lithium
MessagePerformed in Chemistry
Performed at Sonora Quest Laboratories for BPMC
Performed at WyMCC for TCH, PCMH
Performed at SRMC for OCH
Performed at BBMC for BIMC, BGFMC
Performed at Sonora Quest Laboratories for BPMC
Performed at WyMCC for TCH, PCMH
Performed at SRMC for OCH
Performed at BBMC for BIMC, BGFMC
Test Code
LI
CPT Codes
80178
Preferred Specimen
Serum - Red or SST/Gold
BUMCT - NaHep or grey
BUMCT - NaHep or grey
Instructions
For BPMC, see link below for specimen details, methodology, setup schedule and reference ranges.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Collected in an outdated/expired tube
Hemolyzed, icteric or lipemic
Contaminated
Hemolyzed, icteric or lipemic
Contaminated
FDA Status
FDA Approved
Setup Schedule
Daily, Sunday through Saturday
Report Available
Less than 4 hours
Clinical Significance
Lithium is widely used in the treatment of manic depressive psychosis. Administered as lithium carbonate, it is completely absorbed by the gastro-intestinal tract; peak serum levels occur 2 to 4 hours after an oral dose. The half life in serum is 48 to 72 hours and it is cleared through the kidneys (excretion parallels that of sodium). Reduced renal function can prolong clearance time. Lithium acts by enhancing the uptake of neurotransmitters, which produces a sedative effect on the central nervous system. Serum lithium concentrations are measured essentially to ensure compliance and to avoid toxicity. Early symptoms of intoxication include apathy, sluggishness, drowsiness, lethargy, speech difficulties, irregular tremors, myoclonic twitchings, muscle weakness and ataxia. Levels higher than 1.5 mmol/L (12 hours after a dose) indicate a significant risk of intoxication.
Additional Information
Lithium
