Gentamicin, Trough

Message

Performed in Chemistry
Performed at SQL for Page and BBMC.
Performed at BDMC for Payson and BCGMC.
Performed at WyMCC for WMC, TCH and PCMH.

Test Code

GENTT

CPT Codes
80170

Preferred Specimen

Green LiHep, Plasma
WyMCC, WMC, TCH, PCMH - SST
Page and BBMC - Red

Other Acceptable Specimens

Red, Gold/SST

Instructions

Draw specimen just before next dose.
For facilities sending to SQL, see link below for specimen details, methodology, setup schedule and reference ranges.

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Collected in an outdated/expired tube
Hemolyzed, icteric or lipemic
Contaminated

FDA Status
FDA Approved

Setup Schedule

Daily, Sunday through Saturday

Report Available

Less than 4 hours

Clinical Significance

Gentamicin is used in the treatment of serious infections involving aminoglycosidesensitive organisms. Monitoring gentamicin concentration in serum or plasma, along with careful clinical assessment, is the most effective means of ensuring adequate therapy. Gentamicin concentration correlates better with antibacterial activity than dosage. A standard dose of gentamicin does not always yield a predictable concentration because drug concentration depends on patient’s volume of distribution and on drug elimination. The mode of administration, the volume of extracellular fluid, renal retention, and physiological change influence these factors during therapy. Gentamicin has a narrow range of safe and effective concentration. Exposure to high concentrations for a prolonged period may cause renal impairment or ototoxicity. Patients with impaired renal function should be monitored closely while on gentamicin therapy because nephrotoxicity caused by gentamicin may be difficult to distinguish from symptoms of underlying renal disease.1

Additional Information
Gentamicin, Trough

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.