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Acetaminophen
MessagePerformed in Chemistry
Test Code
ACETA
Alias/See Also
Tylenol
CPT Codes
80329
Preferred Specimen
Green Top LiHep, Plasma
WyMCC - SST
WyMCC - SST
Other Acceptable Specimens
Gold/SST or Red Top
Specimen Stability
Room Temperature 24 hr
Refrigerated 7 days
Frozen 6 months
Refrigerated 7 days
Frozen 6 months
FDA Status
FDA Approved
Setup Schedule
Daily, Sunday through Saturday
Report Available
Less than 4 hours
Clinical Significance
Acetaminophen is a widely used analgesic and antipyretic found in a number of over‑the‑counter and prescription products. When consumed in overdose quantities, acetaminophen may cause severe liver and kidney damage, or death. The patient may have few or no symptoms early after acute overdose of acetaminophen. The only reliable early diagnostic indicator is provided by a quantitative measurement of the serum acetaminophen level. Clinical evidence of liver and kidney damage is usually delayed for 24 hours or more after ingestion, well after the time that the prophylactic antidote, acetylcysteine, can be effectively administered. Acetylcysteine is highly effective in preventing liver damage, especially if administered within 8 to 10 hours after overdose, and improves survival in patients with hepatic failure when initiated 12 to 16 hours after overdose.