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Fentanyl Screen
Test CodeFENTSCUR
CPT Codes
80354
Preferred Specimen
15 mL Urine - first morning (best) or random collection
Sterile or yellow top urine tube
Sterile or yellow top urine tube
Minimum Volume
1.0 mL Random Urine
Transport Temperature
Refrigerated
Specimen Stability
Temperature Stability
15-25 °C 14 days
2-8 °C 14 days
-15 – -25°C 30 days
Sample Retention: 1 week
15-25 °C 14 days
2-8 °C 14 days
-15 – -25°C 30 days
Sample Retention: 1 week
Setup Schedule
7 days a week
Report Available
Same day
Clinical Significance
Fentanyl is a synthetic narcotic analgesic of high potency and short duration of action. Although 200 times more potent than Morphine, Fentanyl has a high safety margin. The drug is available as a citrate salt in an injectable solution containing 50 µg/mL. It is also available as a transdermal patch containing 2.5 – 10 mg Fentanyl and provides a dose of 25 – 100 µg/hr for 72 hours for management of chronic pain. While Fentanyl has all the properties of Morphine, it is structurally different and therefore cannot be detected by screening tests for Morphine and related opiates. Because of the potency of the drug, concentrations encountered in biological fluids are in the sub nanogram range.
