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Creatinine Clearance Adult
MessagePerformed in Chemistry
Plasma/Serum and Urine are required.
Plasma/Serum and Urine are required.
Test Code
CRCLA
Alias/See Also
CRCLP
PECAL
24 Hr
PECAL
24 Hr
Preferred Specimen
1 mL plasma from Green top (Lithium Heparin), WyMCC - SST
AND
Entire specimen or 10 mL well mixed aliquot from 24 hour Urine Collection
AND
Entire specimen or 10 mL well mixed aliquot from 24 hour Urine Collection
Minimum Volume
0.5 mL plasma or serum
0.5 mL urine
0.5 mL urine
Other Acceptable Specimens
1 mL serum from SST or Red Top
Instructions
Creatinine Clearances are performed on 24-hour urine collections only. Cerner will need a serum creatinine for calculations:
• Cerner will use a serum creatinine result if available in the chart from last 48 hours.
• If there is no serum creatinine result from the last 48 hours and a serum creatinine is ordered within the next 24 hours, a CREAT4CLR will NOT be ordered.
• If there is no serum creatinine result in the last 48 hours and one is not ordered within the next 24 hours, CREAT4CLR will be automatically ordered.
• Height and Weight are required for processing.
• Refrigerate specimen during collection.
• Starting and ending times of collection are required for processing.
• Total Volume is required for processing.
• Cerner will use a serum creatinine result if available in the chart from last 48 hours.
• If there is no serum creatinine result from the last 48 hours and a serum creatinine is ordered within the next 24 hours, a CREAT4CLR will NOT be ordered.
• If there is no serum creatinine result in the last 48 hours and one is not ordered within the next 24 hours, CREAT4CLR will be automatically ordered.
• Height and Weight are required for processing.
• Refrigerate specimen during collection.
• Starting and ending times of collection are required for processing.
• Total Volume is required for processing.
FDA Status
FDA Approved
Setup Schedule
Daily, Sunday through Saturday
Report Available
Less than 4 hours
Clinical Significance
Creatinine is an endogenous substance most commonly used to measure the glomerular filtration rate (GFR) of the
kidneys. The linear decrease of creatinine clearance over time, as renal function fails, has been thoroughly documented
for several forms of chronic glomerulonephritis (including chronic membranous glomerular nephritis, diabetic
nephropathy, chronic interstitial nephritis, and at least some cases of chronic pyelonephritis).
kidneys. The linear decrease of creatinine clearance over time, as renal function fails, has been thoroughly documented
for several forms of chronic glomerulonephritis (including chronic membranous glomerular nephritis, diabetic
nephropathy, chronic interstitial nephritis, and at least some cases of chronic pyelonephritis).