Cortisol, Free, LC/MS, Serum

Message

This test is currently only available in BHS CPRS. If you are a Bedford provider and wish to see this test offered in Bedford CPRS- please contact the Bedford Laboratory. Testing performed at Quest Diagnostics.
TEST PERFORMED ON PLASMA.

Test Code

CORTISOL FREE,PL(O)

CPT Codes
82530

Preferred Specimen

2 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.7 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube or PPT potassium (white-top) tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 2 years

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Received room temperature • Serum separator tube (SST)

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Night

Reference Range

Adult
8:00 - 10:00 A.M.	0.07-0.93 mcg/dL
4:00 - 6:00 P.M.	0.04-0.45 mcg/dL
10:00- 11:00 P.M.	0.04-0.35 mcg/dL

Clinical Significance

Free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated.

Last Updated: September 16, 2019

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.