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MGMT Methylation,PCR
Test CodeMGMT METHYLATION,PCR(o)
Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block submitted in a tissue transport kit.
Other Acceptable Specimens
5 unstained 5-micron slides submitted in a tissue transport kit.
Instructions
Include surgical pathology report. Tissue block will be returned after testing.
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable
Refrigerated: Indefinitely
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Specimens fixed/processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5)
Decalcified specimens
Less than 25 percent tumor
Decalcified specimens
Less than 25 percent tumor
Methodology
Real-Time Polymerase Chain
Reaction/Fluorescence Resonance
Energy Transfer
Setup Schedule
Daily
Report Available
10-12 days
Clinical Significance
Aids in therapeutic decisions in individuals with gliomas.
Last Updated: December 13, 2018
