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Fungitell® ß-D-Glucan Assay (Fluid)

Message
This test is currently only available in BHS CPRS. If you are a Bedford provider and wish to see this test offered in Bedford CPRS- please contact the Bedford Laboratory.


Test Code
BETA D-GLUCAN,FLUID(O)


Preferred Specimen
Bronchial Alveolar Lavage
Bronchial Wash
Cerebrospinal Fluid


Minimum Volume
Preferred: 2mL
Minimum: 0.1mL


Specimen Stability
Refrigerated: 5 days
Freeze if testing > 5 days.


Methodology
The assay is based upon a modification of the Limulus Amebocyte Lysate (LAL) pathway. The key assay reagent is modified to eliminate Factor C, and is therefore specific for (1,3)- ß-D-glucan and does not react to other polysaccharides, including beta-glucans with different glycosidic linkages. Similar to enzyme immunoassays, the Fungitell ß-D Glucan assay is performed in microplates and read in an incubating reader. This test has been cleared or approved for diagnostic use by the U.S. Food and Drug Administration.

Reference Range
Provided with patient report in CPRS.


Clinical Significance
There is an increasing incidence of fungal infections by opportunistic pathogens, especially in immunocompromised patients.1-3 Invasive fungal diseases, as opportunistic infections, are common among hematological malignancy and AIDS patients and account for a growing number of nosocomial infections, particularly among organ transplant recipients and other patients receiving immunosuppressive treatments.4,5 Many fungal diseases are acquired by inhaling fungal spores originating from the soil, plant detritus, air-handling systems and/or exposed surfaces. Some opportunistic fungi are present in/on human skin, the intestinal tract, and mucous membranes.6,7 Diagnosis of invasive mycoses and fungemias is usually based on non-specific diagnostic or radiological techniques. Recently, biological markers of fungal infection have been added to the available diagnostic methods.8


Performing Laboratory
Viracor Eurofins

Additional Information
Link to Viracor-Eurofins Test Menu

Last Updated: June 22, 2018


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.