Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay, Serum

Message

This test is currently only available in BHS CPRS. If you are a Bedford provider and wish to see this test offered in Bedford CPRS- please contact the Bedford Laboratory. Testing performed at Quest Diagnostics.

Test Code

AQUAPORIN 4(O)

CPT Codes
86053

Includes

When the results of this assay require further evaluation, NMOTS / Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Titer Assay, Serum will be performed at an additional charge.

Preferred Specimen

2 mL serum

Minimum Volume

2 mL

Instructions

Include relevant clinical information, name, phone number, mailing address, and e-mail address (if applicable) of ordering physician.

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 72 hours
Refrigerated: 28 days
Frozen: 28 days

Methodology
Flow Cytometry

Setup Schedule

Set up: Mon, Tues, Thurs; Report available: 5-8 days

Reference Range

Negative

Clinical Significance

Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD) Diagnosis of autoimmune AQP4 channelopathy. Distinguishing NMOSD from multiple sclerosis early in the course of disease.

Last Updated: January 16, 2018

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.