Helicobacter pylori Antigen, Stool

Curian HpSA, for use with the Curian Analyzer is a rapid, qualitative, fluorescent immunoassay for the detection of Helicobacter pylori antigen in human stool.  Test results are intended to aid in the diagnosis of H. pylori infection and to demonstrate loss of H. pylori antigen following treatment.  Accepted medical practice recommends that testing by any current method, to confirm eradication, be done at least four weeks following completion of therapy. Test results should be taken into consideration by the physician in conjunction with the patient history and symptoms.

H.PYLORI AG,STOOL

Solid or formed, semisolid and liquid stool samples are acceptable.

Antimicrobials, proton pump inhibitors and bismuth preparations are known to suppress H. pylori and ingestion of these prior to H. pylori testing (culture, histology, rapid urease, UBT, antigen) may give a false negative result.  If a negative result is obtained for a patient ingesting these compounds within two weeks prior to performing the Curian HpSA assay, a false-negative result may be obtained.  The test should be repeated on a new specimen two weeks after discontinuing treatment. A positive result for a patient ingesting these compounds within two weeks prior to performing the Curian HpSA test, should be considered accurate.

2-8°C for 72 hrs or frozen at -20° for up to 14 days.

QNS
DO NOT USE STOOL IN TRANSPORT MEDIA, OR SWABS, OR MIXED WITH PRESERVATIVES.
 

Interfering substances:
The following substances were found to have no effect on results when present in stool at the concentrations indicated.

Tums® Antacid (5 mg/mL), Tagamet® (5 mg/mL), Prilosec® (5 mg/mL), Mylanta® Antacid (1:20), Pepto-Bismol® (1:20), Barium sulfate (5%), Whole Blood (50%), Leukocytes (50%), Mucin (3.4%), Stearic acid/palmitic acid (fecal fat) (4%), Hemoglobin (tarry stool) (12.5%)

Neg