Cortisol, Free, LC/MS, Serum

Message

This test is currently only available in Bedford CPRS. If you are a BHS provider and wish to see this test offered in BHS CPRS- please contact the BHS Laboratory.

Test Code

CORTISOL,FREE(O)

CPT Codes
82530

Preferred Specimen

2 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.7 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top), or PPT potassium EDTA (white-top) tube

Transport Container

Plastic screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 2 years

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Serum separator tube (SST)

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Sun-Thurs; Report available: 4-8 days

Reference Range

Adult
8:00 - 10:00 A.M.	0.07-0.93 mcg/dL
4:00 - 6:00 P.M.	0.04-0.45 mcg/dL
10:00- 11:00 P.M.	0.04-0.35 mcg/dL

Clinical Significance

Free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated.

Last Updated: October 20, 2015

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.