Epstein-Barr Virus DNA, Qualitative Real-Time PCR

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If CJD is suspected - please contact the Laboratory 

This test is currently only available in BHS CPRS. If you are a Bedford provider and wish to see this test offered in Bedford CPRS- please contact the Bedford Laboratory.
Test performed at Quest Diagnostics.


Test Code
EBV QUAL PCR,CSF(O)


CPT Codes
87798

Preferred Specimen
1 mL whole blood or plasma collected in an EDTA (lavender-top) tube or
1 mL serum, or
1 mL CSF collected in a sterile plastic leak-proof container, or
> 3 cubic mm fresh tissue collected in a sterile plastic leak-proof container


Minimum Volume
0.3 mL


Other Acceptable Specimens
Body fluids (amniotic fluid, ocular fluid), lower respiratory specimens (BAL, bronchial wash, tracheal secretions) collected in a sterile plastic leak-proof container


Instructions
CSF: Collect in a sterile, plastic container and store refrigerated or frozen
Tissue: Collect in a sterile, plastic container and transport frozen
⁠⁠⁠⁠⁠⁠⁠
Do not freeze whole blood


Transport Temperature
Tissue: Frozen
All other sample types: Refrigerated (cold packs)


Specimen Stability
Whole blood
Room temperature: 48 hours
Refrigerated: 8 days
Frozen: Unacceptable

All other specimens
Room temperature: 48 hours
Refrigerated: 8 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed whole blood • Heparin whole blood


Methodology
Real-Time Polymerase Chain Reaction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Daily; Report available: 1 day


Reference Range
Not detected


Clinical Significance
Infection with EBV is common and is generally subclinical or presents as a self-limited illness. Reactivation of latent EBV in an immunocompromised person can lead to more serious results, including lymphoproliferative disorders or neurological disease. PCR methods may be useful in identifying EBV in a variety of clinical specimens.



Last Updated: June 6, 2016


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.