T-Cell Receptor Gene Rearrangement, CSF

Message

If CJD is suspected - please contact the Laboratory.

This test is currently only available in BHS CPRS. If you are a Bedford provider and wish to see this test offered in Bedford CPRS- please contact the Bedford Laboratory.

Test Code

TCR GENE,CSF(O)

Preferred Specimen

CSF

Minimum Volume

5mL

Transport Temperature

Refrigerated

Methodology
PCR

Report Available

7-14 days

Reference Range

Provided with the patient report in CPRS.

Clinical Significance

The T-cell receptor (TCR) genes (alpha, beta, delta, and gamma) are comprised of numerous, discontinuous coding segments that somatically rearranged to produce heterodimeric cell surface T-cell receptors, either alpha/beta (90%-95% of T cells) or gamma/delta (5%-10% of T cells). With rare exceptions (eg, some neoplastic B-lymphoid proliferations), other cell types retain the "germline" configuration of the TCR genes without rearrangement.

Performing Laboratory
Test performed at Mayo Clinic and sent via Quest.

Additional Information
Link to test information on Mayo Clinic website

Last Updated: October 28, 2015

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.