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Human Anti-mouse Antibody (HAMA)
MessageThis test is currently only available in BHS CPRS. If you are a Bedford provider and wish to see this test offered in Bedford CPRS- please contact the Bedford Laboratory.
Testing performed at Quest Diagnostics.
Testing performed at Quest Diagnostics.
Test Code
HAMA(O)
CPT Codes
83520
Preferred Specimen
1 mL frozen serum collected in a red-top tube (no gel)
Minimum Volume
0.5 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 24 hours
Frozen -20°C: 21 days
Frozen -70°C: 90 days
Refrigerated: 24 hours
Frozen -20°C: 21 days
Frozen -70°C: 90 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross lipemia • Serum separator tube (SST)
Methodology
Enzyme Linked Immunosorbent Assay (ELISA)
Setup Schedule
Set up: Thurs; Report available: 7-14 days
Reference Range
≤74 ng/mL
Clinical Significance
The presence of Human Anti-mouse Antibody (HAMA) has been associated with patients receiving injections of Murine Monoclonal Antibody (MAB) for diagnostics and/or therapeutic purposes. HAMA produced in response to monoclonal antibody therapy may interfere with therapeutic efficacy. Therefore, it is recommended that baseline HAMA levels are determined prior to the initiation of therapy with murine-derived proteins.
Last Updated: September 20, 2014
